Genomic Data Infrastructure

Contact person: Stefania Boccia

Short Title: GDI

Call: EU Framework Programme for Research and Innovation, DIGITAL EUROPE

Project Code: 101081813

Start date: 01/11/2022

End date: 01/11/2026

Coordinator: European Molecular Biology Laboratory

Funding body: EUROPEAN UNION

Link: https://gdi.onemilliongenomes.eu/

Abstract: The Genomic Data Infrastructure (GDI) project is enabling access to genomic, phenotypic and related clinical data across Europe. It does this by creating a federated, sustainable and secure infrastructure for sharing and accessing this data. The project builds on the achievements of Beyond 1 Million Genomes (B1MG) and contributes to realising the ambition of the 1+Million Genomes (1+MG) initiative. The data
The project concerns human genomic data and related phenotypic and clinical data, stored in databases distributed throughout Europe. The initiative will focus on the Genome of Europe (a network of national collections of reference genomes) and use cases related to cancer and infectious diseases. For the validation phase, "realistic" synthetic data will be used, waiting for the real data to be accessible through the infrastructure.

Who will be able to access it?
Controlled access will be granted to approved clinicians and scientists, from both the public and private sectors, as well as health policy makers. Non-sensitive and aggregated data will be freely available through the European Genome Dashboard and a federated query system. This system will support genotypic and phenotypic research formulated in natural language.

What are the benefits?
The insights from the data will help improve clinical diagnostics, treatments and predictive medicine for European citizens. The project will also lead to more effective public health measures, benefiting citizens, health systems and the economy.

Who manages it?
The GDI project brings together experts in life sciences, medicine, computer science, ethics and law, from 54 partners in 20 countries and two infrastructure organisations. They will ensure that access to datasets is secure, ethical and compliant with European and national regulations.